Discussion
Diagnosis With Brief Discussion
- Diagnosis
- MALT lymphoma
- Radiologic Findings
- Figure 1. Consolidation is demonstrated on chest CT scanned 5 years ago.
Figure 2 and 3. Chest CT images with lung and mediastinal window setting show consolidation with ground glass opacity and interstitial thickening in left upper lobe, lingular division. In comparison with previous CT, these lesions are slowly increasing in extent. Pleural retraction and air-bronchogram are also noted.
Figure 4 and 5. Follow up axial and coronal chest CT images obtained after 3 weeks show no appreciable change of the lesion.
Figure 6. Subsequent PET CT demonstrates FDG uptake in the lesion.
- Brief Review
- MALT lymphoma (MALToma) is a monoclonal lymphoid proliferation arising from a B-cell progenitor within the BALT, and is classified as low-grade marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue in the World Health Organization (WHO) classification. Histologically, MALT lymphoma is a lesion comprised of sheets of monoclonal lymphocytes with occasional interspersed plasma cells.
The radiologic features of BALT lymphomas do not differ from those of other pulmonary lymphomas. Most commonly, lesions consist of masses, masslike areas of consolidation, or pulmonary nodules. On PET/CT, BALT lymphomas may or may not show increased uptake of FDG. Air bronchograms and enhancing vessels through the masses can be observed. Pleural effusion and thickening, cavitation, and hilar and mediastinal lymphadenopathy are not commonly seen.
- Please refer to
Case 851, Case 1032, Case 1049, Case 1071, Case 1108, -
- References
- 1. Sirajuddin, Arlene, et al. "Primary pulmonary lymphoid lesions: radiologic and pathologic findings." Radiographics 36.1 (2016): 53-70.
2. Hayashi, Daichi, et al. "Mucosa-associated lymphoid tissue lymphoma: multimodality imaging and histopathologic correlation." American Journal of Roentgenology 195.2 (2010): W105-W117.
- Keywords
- Lung, Neoplasm_Malignant, Lymphoma,